I am Professor of Clinical Oncology and Breast Cancer Genetics at King’s College London. I trained in medicine at UCL and decided to specialise in oncology after working at Mount Vernon Hospital as a junior doctor. I undertook a PhD in molecular genetics at the London Research Institute and then trained as a clinician scientist.
My research interests are genetic predisposition to breast cancer, particularly lobular breast cancer and DCIS, and identification of biomarkers that predict progression of LCIS and DCIS. I set up two large case control studies (~6000 participants) in DCIS and lobular breast cancer funded by CRUK to assess genetic predisposition in these two cancer subtypes. This led to the identification of 7q34 as a lobular specific predisposition locus.
My clinical practice is based at Guys and St Thomas Foundation Trust where I specialise in radiotherapy and systemic therapy for breast cancer particularly ER+ breast cancer. I strongly support the work that LBCUK is doing as lobular breast cancer is a unique breast cancer subtype that requires dedicated research and clinical trials in order to improve outcomes in ILC.